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1

The microtubule targeting agents eribulin and paclitaxel activate similar signaling pathways and induce cell death predominantly in a caspase-independent manner

Hüsemann, Lisa C., Reese, Alina, Radine, Claudia, Piekorz, Roland P., Budach, Wilfried, Sohn, Dennis, Jänicke, Reiner U.

Journal:

Year:

2020

File:

PDF, 5.39 MB

2020

2

Deficiency of PI3-Kinase catalytic isoforms p110γ and p110δ in mice enhances the IL-17/G-CSF axis and induces neutrophilia

Bucher, Kirsten, Schmitt, Fee, Mothes, Benedikt, Blumendeller, Carolin, Schäll, Daniel, Piekorz, Roland, Hirsch, Emilio, Nürnberg, Bernd, Beer-Hammer, Sandra

Journal:

Cell Communication and Signaling

Year:

2017

Language:

english

File:

PDF, 2.33 MB

english, 2017

3

Functional Reconstitution of IL-6 Signaling in a Myeloid Leukemic Cell Line

P. WULF, R. P. PIEKORZ, G. M. HOCKE

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 174 KB

english, 1995

4

Long-term simulations of particulate matter in Europe on different scales using sequential nesting of a regional model

Memmesheimer, M., Friese, E., Ebel, A., Jakobs, H.J., Feldmann, H., Kessler, C., Piekorz, G.

Journal:

International Journal of Environment and Pollution

Year:

2004

Language:

english

File:

PDF, 3.43 MB

english, 2004

5

The Impact Of Pelvic Floor Muscle Training On Urinary Incontinence In Men After Radical Prostatectomy (RP) – A Systematic Review

Strączyńska, Agnieszka, Weber-Rajek, Magdalena, Strojek, Katarzyna, Piekorz, Zuzanna, Styczyńska, Hanna, Goch, Aleksander, Radzimińska, Agnieszka

Journal:

Clinical Interventions in Aging

Year:

2019

File:

PDF, 547 KB

2019

6

The catalytic phosphoinositol 3-kinase isoform p110δ is required for glioma cell migration and invasion

Sze Ki Luk, Roland P. Piekorz, Bernd Nürnberg, Shing-Shun Tony To

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 816 KB

english, 2012

7

Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes

Cirstea, I. C., Gremer, L., Dvorsky, R., Zhang, S.-C., Piekorz, R. P., Zenker, M., Ahmadian, M. R.

Journal:

Human Molecular Genetics

Year:

2013

Language:

english

File:

PDF, 368 KB

english, 2013

8

The impact of pelvic floor muscle training on the quality of life of women with urinary incontinence: a systematic literature review

Radzimińska, Agnieszka, Strączyńska, Agnieszka, Weber-Rajek, Magdalena, Styczyńska, Hanna, Strojek, Katarzyna, Piekorz, Zuzanna

Journal:

Clinical Interventions in Aging

Year:

2018

Language:

english

File:

PDF, 510 KB

english, 2018

9

Selective protection of murine cerebral Gi/o-proteins from inactivation by parenterally injected pertussis toxin

Vega, Salvador Castaneda, Leiss, Veronika, Piekorz, Roland, Calaminus, Carsten, Pexa, Katja, Vuozzo, Marta, Schmid, Andreas M., Devanathan, Vasudharani, Kesenheimer, Christian, Pichler, Bernd J., Beer

Journal:

Journal of Molecular Medicine

Year:

2019

File:

PDF, 1.36 MB

2019

10

INDUCTION OF DIFFERENTIATION BY IL-6-TYPE CYTOKINES IS IMPAIRED IN MYELOID LEUKAEMIA CELLS UNABLE TO ACTIVATE Stat5a

Roland P. Piekorz, Gertrud M. Hocke

Journal:

Year:

1997

Language:

english

File:

PDF, 310 KB

english, 1997

11

The Transforming Acidic Coiled Coil 3 Protein Is Essential for Spindle-dependent Chromosome Alignment and Mitotic Survival

Schneider, L., Essmann, F., Kletke, A., Rio, P., Hanenberg, H., Wetzel, W., Schulze-Osthoff, K., Nurnberg, B., Piekorz, R. P.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.10 MB

english, 2007

12

A Randomized-Controlled Trial Pilot Study Examining the Effect of Pelvic Floor Muscle Training on the Irisin Concentration in Overweight or Obese Elderly Women with Stress Urinary Incontinence

Weber-Rajek, Magdalena, Radzimińska, Agnieszka, Strączyńska, Agnieszka, Strojek, Katarzyna, Piekorz, Zuzanna, Kozakiewicz, Mariusz, Styczyńska, Hanna

Journal:

BioMed Research International

Year:

2019

Language:

english

File:

PDF, 1.71 MB

english, 2019

13

Modulation of 2-Adrenoceptor Functions by Heterotrimeric G i Protein Isoforms

Albarran-Juarez, J., Gilsbach, R., Piekorz, R. P., Pexa, K., Beetz, N., Schneider, J., Nurnberg, B., Birnbaumer, L., Hein, L.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2009

Language:

english

File:

PDF, 2.00 MB

english, 2009

14

Regulation of Progesterone Levels during Pregnancy and Parturition by Signal Transducer and Activator of Transcription 5 and 20α-Hydroxysteroid Dehydrogenase

Piekorz, Roland P., Gingras, Sébastien, Hoffmeyer, Angelika, Ihle, James N., Weinstein, Yacob

Journal:

Molecular Endocrinology

Year:

2005

Language:

english

File:

PDF, 345 KB

english, 2005

15

A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: Insights from gene expression profiling

Martina Gatzka, Roland Piekorz, Richard Moriggl, Jason Rawlings, James N. Ihle

Journal:

Year:

2006

Language:

english

File:

PDF, 1.80 MB

english, 2006

16

Differential Modulation Of Cardiac L-type Calcium Currents By GαI2 And GαI3

Dizayee, Sara, Kaestner, Sonja, Felda, Olga, Piekorz, Roland, Meszaros, Janos, Matthes, Jan, Nürnberg, Bernd, Herzig, Stefan

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

17

662 Mitotic spindle stress elicited by TACC3 depletion as a major trigger of premature senescence

S. Schmidt, L. Schneider, F. Essmann, I.C. Cirstea, A. Lindecke, F. Kuck, R.U. Jähnicke, M.R. Ahmadian, K. Schulze-Osthoff, R.P. Piekorz

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

18

The Centrosomal, Putative Tumor Suppressor Protein TACC2 Is Dispensable for Normal Development, and Deficiency Does Not Lead to Cancer

Schuendeln, M. M., Piekorz, R. P., Wichmann, C., Lee, Y., McKinnon, P. J., Boyd, K., Takahashi, Y., Ihle, J. N.

Journal:

Molecular and Cellular Biology

Year:

2004

Language:

english

File:

PDF, 452 KB

english, 2004

19

Gadd45 Is Dispensable for Normal Mouse Development and T-Cell Proliferation

Hoffmeyer, A., Piekorz, R., Moriggl, R., Ihle, J. N.

Journal:

Molecular and Cellular Biology

Year:

2001

Language:

english

File:

PDF, 331 KB

english, 2001

20

p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation

Mothes, Benedikt, Bucher, Kirsten, Ammon-Treiber, Susanne, Schwab, Matthias, Piekorz, Roland P., Hirsch, Emilio, Nürnberg, Bernd, Beer-Hammer, Sandra, Fehrenbach, Heinz

Journal:

Year:

2016

Language:

english

File:

PDF, 7.14 MB

english, 2016

21

PI3Kδ is indispensable for CTL-mediated cytotoxicity

Eva M Putz, Michaela Prchal, Olivia Simma, Florian Forster, Xaver Koenig, Roland Piekorz, Michael Freissmuth, Veronika Sexl, Eva-Maria Zebedin

Journal:

BMC Pharmacology

Year:

2011

Language:

english

File:

PDF, 92 KB

english, 2011

22

Correction: p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation

Mothes, Benedikt, Bucher, Kirsten, Ammon-Treiber, Susanne, Schwab, Matthias, Piekorz, Roland P., Hirsch, Emilio, Nürnberg, Bernd, Beer-Hammer, Sandra

Journal:

Year:

2016

Language:

english

File:

PDF, 3.01 MB

english, 2016

23

Short-term outcomes of endovascular repair of abdominal aortic aneurysm, including ruptured cases

Kulig, Piotr, Lewandowski, Krzysztof, Banaś, Bartłomiej, Piekorz, Piotr, Kostka, Andrzej, Zaniewski, Maciej

Journal:

Videosurgery and Other Miniinvasive Techniques

Year:

2018

Language:

english

File:

PDF, 91 KB

english, 2018

24

MAST CELL-RESTRICTED p70 STAT6 ISOFORM IS A PRODUCT OF SELECTIVE PROTEOLYSIS

Christopher P. Shelburne, Roland P. Piekorz, L.Andrew Bouton, Hey Jin Chong, John J. Ryan

Journal:

Year:

2002

Language:

english

File:

PDF, 516 KB

english, 2002

25

Ammonia inhibits energy metabolism in astrocytes in a rapid and glutamate dehydrogenase 2-dependent manner

Drews, Leonie, Zimmermann, Marcel, Westhoff, Philipp, Brilhaus, Dominik, Poss, Rebecca E., Bergmann, Laura, Wiek, Constanze, Brenneisen, Peter, Piekorz, Roland P., Mettler-Altmann, Tabea, Weber, Andre

Journal:

Disease Models & Mechanisms

Year:

2020

File:

PDF, 4.89 MB

2020

26

PI3Kδ: a double-edged sword in leukemia formation

Eva-Maria Zebedin, Olivia Simma, Christian Schuster, Eva Eckelhart, Wolgang Warsch, Dagmar Stoiber, Eva Weisz, Winfried F Pickl, Roland Piekorz, Michael Freissmuth, Veronika Sexl

Journal:

BMC Pharmacology

Year:

2007

Language:

english

File:

PDF, 79 KB

english, 2007

27

Defective Macrophage Migration in G i2- but Not G i3-Deficient Mice

Wiege, K., Le, D. D., Syed, S. N., Ali, S. R., Novakovic, A., Beer-Hammer, S., Piekorz, R. P., Schmidt, R. E., Nurnberg, B., Gessner, J. E.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 653 KB

english, 2012

28

Dissecting the role of INCENP-Aurora B in spindle assembly checkpoint function, chromosomal alignment and cytokinesis

Piekorz, Roland P.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.56 MB

english, 2010

29

An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver

Gohla, A., Klement, K., Piekorz, R. P., Pexa, K., vom Dahl, S., Spicher, K., Dreval, V., Haussinger, D., Birnbaumer, L., Nurnberg, B.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 1.64 MB

english, 2007

30

PI3Kδ Is Essential for Tumor Clearance Mediated by Cytotoxic T Lymphocytes

Putz, Eva Maria, Prchal-Murphy, Michaela, Simma, Olivia Annabella, Forster, Florian, Koenig, Xaver, Stockinger, Hannes, Piekorz, Roland P., Freissmuth, Michael, Müller, Mathias, Sexl, Veronika, Zebedi

Journal:

Year:

2012

Language:

english

File:

PDF, 728 KB

english, 2012

31

Modulation of the activation status of Stat5a during LIF-induced differentiation of M1 myeloid leukemia cells

Roland P Piekorz, Ralf Rinke, Fabrice Gouilleux, Brigitte Neumann, Bernd Groner, Gertrud M Hocke

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1998

Language:

english

File:

PDF, 400 KB

english, 1998

32

Stat5 Activation Is Uniquely Associated with Cytokine Signaling in Peripheral T Cells

Richard Moriggl, Veronika Sexl, Roland Piekorz, David Topham, James N Ihle

Journal:

Year:

1999

Language:

english

File:

PDF, 238 KB

english, 1999

33

Platelet G i protein Gα i2 is an essential mediator of thrombo-inflammatory organ damage in mice

Devanathan, Vasudharani, Hagedorn, Ina, Köhler, David, Pexa, Katja, Cherpokova, Deya, Kraft, Peter, Singh, Madhurendra, Rosenberger, Peter, Stoll, Guido, Birnbaumer, Lutz, Piekorz, Roland P., Beer-Ham

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

34

New Model for Gastroenteropancreatic Large-Cell Neuroendocrine Carcinoma: Establishment of Two Clinically Relevant Cell Lines

Krieg, Andreas, Mersch, Sabrina, Boeck, Inga, Dizdar, Levent, Weihe, Eberhard, Hilal, Zena, Krausch, Markus, Möhlendick, Birte, Topp, Stefan A., Piekorz, Roland P., Huckenbeck, Wolfgang, Stoecklein, N

Journal:

Year:

2014

Language:

english

File:

PDF, 2.12 MB

english, 2014

35

The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

Journal:

The EMBO Journal

Year:

2002

Language:

english

File:

PDF, 406 KB

english, 2002

36

Kinetics of the Activation of the LIF?Response Factor in M1 Myeloid Leukemic Cells

R. P. PIEKORZ, R. BLÄSIUS, G. H. FEY, G. M. HOCKE

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 166 KB

english, 1995

37

The catalytic PI3K isoforms p110 and p110 contribute to B cell development and maintenance, transformation, and proliferation

Beer-Hammer, S., Zebedin, E., von Holleben, M., Alferink, J., Reis, B., Dresing, P., Degrandi, D., Scheu, S., Hirsch, E., Sexl, V., Pfeffer, K., Nurnberg, B., Piekorz, R. P.

Journal:

Journal of Leukocyte Biology

Year:

2010

Language:

english

File:

PDF, 1.75 MB

english, 2010

38

26/Ocena skuteczności brachyterapii HDR w zaawansowanym raku płuca

B. Jochymek, J. Gawełko, W. Piekorz, J. Krypel, R. Kwiatkowski

Journal:

Reports of Practical Oncology & Radiotherapy

Year:

2004

Language:

polish

File:

PDF, 95 KB

polish, 2004

39

Better understanding of phosphoinositide 3-kinase (PI3K) pathways in vasculature: Towards precision therapy targeting angiogenesis and tumor blood supply

Tsvetkov, D., Shymanets, A., Huang, Yu, Bucher, K., Piekorz, R., Hirsch, E., Beer-Hammer, S., Harteneck, C., Gollasch, M., Nürnberg, B.

Journal:

Biochemistry (Moscow)

Year:

2016

Language:

english

File:

PDF, 599 KB

english, 2016

40

Gαi Proteins are Indispensable for Hearing

Beer-Hammer, Sandra, Lee, Sze Chim, Mauriac, Stephanie A., Leiss, Veronika, Groh, Isabel A. M., Novakovic, Ana, Piekorz, Roland P., Bucher, Kirsten, Chen, Chengfang, Ni, Kun, Singer, Wibke, Harasztosi

Journal:

Cellular Physiology and Biochemistry

Year:

2018

Language:

english

File:

PDF, 3.73 MB

english, 2018

41

bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling

Haghighi, Fereshteh, Dahlmann, Julia, Nakhaei-Rad, Saeideh, Lang, Alexander, Kutschka, Ingo, Zenker, Martin, Kensah, George, Piekorz, Roland P., Ahmadian, Mohammad Reza

Journal:

Cell Communication and Signaling

Year:

2018

Language:

english

File:

PDF, 4.84 MB

english, 2018

42

SH3-mediated targeting of Wrch1/RhoU by multiple adaptor proteins

Risse, Sarah L., Vaz, Belen, Burton, Matthew F., Aspenström, Pontus, Piekorz, Roland P., Brunsveld, Luc, Ahmadian, Mohammad R.

Journal:

Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 757 KB

english, 2013

43

Senescence-associated lysosomal α -L-fucosidase (SA- α -Fuc): A sensitive and more robust biomarker for cellular senescence beyond SA- β -Gal

Singh, Madhurendra, Piekorz, Roland P.

Journal:

Year:

2013

Language:

english

File:

PDF, 578 KB

english, 2013

44

MAST CELL-RESTRICTED p70 STAT6 ISOFORM IS A PRODUCT OF SELECTIVE PROTEOLYSIS

SHELBURNE, C, PIEKORZ, R, BOUTON, L, JINCHONG, H, RYAN, J

Journal:

Year:

2002

Language:

english

File:

PDF, 497 KB

english, 2002

45

TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest

Schneider, L, Essmann, F, Kletke, A, Rio, P, Hanenberg, H, Schulze-Osthoff, K, Nürnberg, B, Piekorz, R P

Journal:

Year:

2007

Language:

english

File:

PDF, 379 KB

english, 2007

46

Phosphoinositide 3-Kinases and , Linkers of Coordinate C5a Receptor-Fc Receptor Activation and Immune Complex-induced Inflammation

Konrad, S., Ali, S. R., Wiege, K., Syed, S. N., Engling, L., Piekorz, R. P., Hirsch, E., Nurnberg, B., Schmidt, R. E., Gessner, J. E.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

47

Macrophages Induce the Inflammatory Response in the Pulmonary Arthus Reaction through G i2 Activation That Controls C5aR and Fc Receptor Cooperation

Skokowa, J., Ali, S. R., Felda, O., Kumar, V., Konrad, S., Shushakova, N., Schmidt, R. E., Piekorz, R. P., Nurnberg, B., Spicher, K., Birnbaumer, L., Zwirner, J., Claassens, J. W. C., Verbeek, J. S.,

Journal:

The Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 920 KB

english, 2005

48

The Centrosomal Adaptor TACC3 and the Microtubule Polymerase chTOG Interact via Defined C-terminal Subdomains in an Aurora-A Kinase-independent Manner

Thakur, H. C., Singh, M., Nagel-Steger, L., Kremer, J., Prumbaum, D., Fansa, E. K., Ezzahoini, H., Nouri, K., Gremer, L., Abts, A., Schmitt, L., Raunser, S., Ahmadian, M. R., Piekorz, R. P.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.65 MB

english, 2014

49

Reconstitution of IL6-Inducible Differentiation of a Myeloid Leukemia Cell Line by Activated Stat Factors

Roland Piekorz, Beate Schlierf, Renate Burger, Gertrud M. Hocke

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 724 KB

english, 1998

50

The role of embryonic stem cell-expressed RAS (ERAS) in the maintenance of quiescent hepatic stellate cells

Nakhaei-Rad, Saeideh, Nakhaeizadeh, Hossein, Götze, Silke, Kordes, Claus, Sawitza, Iris, Hoffmann, Michèle J., Franke, Manuel, Schulz, Wolfgang A., Scheller, Jürgen, Piekorz, Roland P., Häussinger, Di

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.49 MB

english, 2016

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